PlainPill

St. John's Wort vs Valerian Root for anxiety

Short answer: For anxiety, users rate them about the same: 82% report improvement with St. John's Wort (44 reports) and 86% with Valerian Root (36 reports).

St. John's Wort has 98 meta-analyses and 111 randomized trials on PubMed; Valerian Root has 2 and 8.

Based on 314 reports about St. John's Wort and 233 about Valerian Root. Not medical advice.

St. John's Wort
Supplement
Valerian Root
Supplement
Users say it helped50%helped151 reports · high confidence57%helped119 reports · high confidence
Verdict
Mixed
Mixed
ResearchAResearch: StrongBResearch: Moderate
Meta-analyses / RCTs98 / 1112 / 8
Mainly used for
Mood
% reporting improvement
87% (127)100% (2)
Sleep
% reporting improvement
89% (9)82% (109)
Anxiety
% reporting improvement
82% (44)86% (36)
Energy
% reporting improvement
60% (10)—
Focus
% reporting improvement
71% (7)—
Common side effectsphotosensitivity, serotonin syndrome, eye problems, dissociationvivid dreams, drowsiness, brain fog, tolerance
Typical dose reported100 mg500 mg / before bed
St. John's Wort
Latest review conclusion

Our research supports the use of SJW as it reduced the number of depressive patients and their HAMD scores while having fewer risks and side effects than conventional medications.

Adv Clin Exp Med, 2023 ↗
What a user said
“St. John's Wort, Passion Flower, Hops, and Skullcap. My sleep improved with those.”
Full St. John's Wort profile →
Valerian Root
Latest review conclusion

In conclusion, valerian could be a safe and effective herb to promote sleep and prevent associated disorders. However, due to the presence of multiple active constituents and relatively unstable nature of some of the active constituents, it may be necessary to revise the quality control processes, including standardization methods and shelf life.

J Evid Based Integr Med, 2020 ↗
What a user said
“I really like lemon balm especially if combined with valerian root! Helps me sleep and relax at night.”
Full Valerian Root profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate