Apigenin vs GABA for sleep
Short answer: For sleep, users rate them about the same: 81% report improvement with Apigenin (77 reports) and 80% with GABA (104 reports).
Apigenin has 36 meta-analyses and 11 randomized trials on PubMed; GABA has 8 and 26.
Based on 277 reports about Apigenin and 470 about GABA. Not medical advice.
| Apigenin Supplement | GABA Supplement | |
|---|---|---|
| Users say it helped | 59%helped94 reports · medium confidence | 40%helped226 reports · high confidence |
| Verdict | Mixed | Mixed |
| Research | AResearch: Strong | AResearch: Strong |
| Meta-analyses / RCTs | 36 / 11 | 8 / 26 |
| Mainly used for | ||
| Sleep % reporting improvement | 81% (77) | 80% (104) |
| Anxiety % reporting improvement | 95% (41) | 80% (122) |
| Mood % reporting improvement | 80% (15) | 67% (21) |
| Hormones % reporting improvement | 100% (12) | 100% (4) |
| Energy % reporting improvement | 57% (7) | 33% (6) |
| Common side effects | vivid dreams, drowsiness, irritability, liver injury | drowsiness, vivid dreams, fatigue, shortness of |
| Typical dose reported | 50 mg | 1500 mg / nightly |
The discovery of the beneficial effects of these natural active compounds in POL supports the idea that POL could be a promising novel candidate for the treatment and prevention of inflammation-related cancers of the digestive system. However, clinical data describing the mode of action of the naturally active compounds of POL are still lacking. In addition, pharmacokinetic data for POL compounds, such as changes in drug dose and absorption rates, cannot be extrapolated from animal models and need to be measured in patients in clinical trials. On the one hand, a systematic meta-analysis of the
J Ethnopharmacol, 2024 ↗“L theanine 200mg, apigenin 50mg, mag theo, mag biglycinate makes me pee too much, GABA 600mg, 3g taurine. I have anxiety and panic disorder late into nights. And this has cured about 80% for me.”
The results provide plausible evidence for the positive role of zinc in the treatment of patients afflicted with anxiety, albeit with some limitations.
Nutr Rev, 2024 ↗“I take 1.5mgs with 1500mg GABA-A Acid I have insane dreams every night and sleep like a baby.”
Related comparisons
Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate