PlainPill

Curcumin vs Quercetin for pain & inflammation

Short answer: For pain & inflammation, more users report improvement with Curcumin — 91% of 104 reports, versus 67% of 15 for Quercetin.

Curcumin has 538 meta-analyses and 553 randomized trials on PubMed; Quercetin has 207 and 232.

Based on 544 reports about Curcumin and 280 about Quercetin. Not medical advice.

Curcumin
Supplement
Quercetin
Supplement
Users say it helped61%helped180 reports · high confidence58%helped67 reports · medium confidence
Verdict
Mostly positive
Mixed
ResearchAResearch: StrongAResearch: Strong
Meta-analyses / RCTs538 / 553207 / 232
Mainly used for
Pain & inflammation
% reporting improvement
91% (104)67% (15)
Mood
% reporting improvement
96% (45)100% (2)
Anxiety
% reporting improvement
93% (15)25% (4)
Immunity
% reporting improvement
100% (3)100% (15)
Focus
% reporting improvement
78% (9)100% (7)
Common side effectsvivid dreams, headache, nausea, dht suppressioninsomnia, jitteriness, anxiety, stimulation
Typical dose reported1000 mg / daily500-1000 mg
Curcumin
Latest review conclusion

Curcumin and Curcuma longa Extract may improve symptoms and inflammation levels in people with arthritis. However, due to the low quality and small quantity of RCTs, the conclusions need to be interpreted carefully.

Front Immunol, 2022 ↗
What a user said
“I recently stopped taking Curcumin because of its affect on DHT and I was looking for an alternative measure to deal with inflammation as I feel it really helped with anxiety/depression.”
Full Curcumin profile →
Quercetin
Latest review conclusion

The results of a meta-analysis of 12 RCTs indicate that TCM intervention can improve the clinical treatment efficacy of CAG. NPAs identified seven hub TCM and 13 target genes associated with their actions, while bioinformatics analysis identified two DEGs between normal and CAG gastric tissues. Finally, molecular docking was employed to reveal the mechanism of action of the active molecules in TCM on the DEGs. These findings not only reveal the mechanisms of action of the active components of the TCMs, but also provide support for the development of new drugs, ultimately blocking the progressi

Ann Med, 2023 ↗
What a user said
“The above supplements have worked amazingly for my brain fog and motivation.”
Full Quercetin profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate