Apigenin vs Chamomile for sleep
Short answer: For sleep, users rate them about the same: 81% report improvement with Apigenin (77 reports) and 85% with Chamomile (46 reports).
Apigenin has 36 meta-analyses and 11 randomized trials on PubMed; Chamomile has 59 and 93.
Based on 277 reports about Apigenin and 122 about Chamomile. Not medical advice.
| Apigenin Supplement | Chamomile Supplement | |
|---|---|---|
| Users say it helped | 59%helped94 reports · medium confidence | 62%helped51 reports · medium confidence |
| Verdict | Mixed | Mostly positive |
| Research | AResearch: Strong | AResearch: Strong |
| Meta-analyses / RCTs | 36 / 11 | 59 / 93 |
| Mainly used for | ||
| Sleep % reporting improvement | 81% (77) | 85% (46) |
| Anxiety % reporting improvement | 95% (41) | 83% (12) |
| Mood % reporting improvement | 80% (15) | — |
| Hormones % reporting improvement | 100% (12) | — |
| Energy % reporting improvement | 57% (7) | — |
| Common side effects | vivid dreams, drowsiness, irritability, liver injury | drowsiness, tolerance with, brain fog, adverse reaction |
| Typical dose reported | 50 mg | 20 mg / before bed |
The discovery of the beneficial effects of these natural active compounds in POL supports the idea that POL could be a promising novel candidate for the treatment and prevention of inflammation-related cancers of the digestive system. However, clinical data describing the mode of action of the naturally active compounds of POL are still lacking. In addition, pharmacokinetic data for POL compounds, such as changes in drug dose and absorption rates, cannot be extrapolated from animal models and need to be measured in patients in clinical trials. On the one hand, a systematic meta-analysis of the
J Ethnopharmacol, 2024 ↗“L theanine 200mg, apigenin 50mg, mag theo, mag biglycinate makes me pee too much, GABA 600mg, 3g taurine. I have anxiety and panic disorder late into nights. And this has cured about 80% for me.”
Chamomile improved sleep, especially the number of awakenings after sleep or staying asleep; however, it did not lead to an improvement in the duration of sleep, percentage of sleep efficiency, and daytime functioning measures. Future studies are suggested to assess objective measures.
Complement Ther Med, 2024 ↗“chamomile significantly improves the clarity of my thought. I also find that I can be a lot more patient, and therefor focus on what I am working on with less distraction.”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate