PlainPill

Alpha-Gpc vs Semax for memory

Short answer: For memory, users rate them about the same: 93% report improvement with Alpha-Gpc (72 reports) and 96% with Semax (53 reports).

Alpha-Gpc has 1 meta-analyses and 13 randomized trials on PubMed; Semax has 0 and 1.

Based on 1,096 reports about Alpha-Gpc and 667 about Semax. Not medical advice.

Alpha-Gpc
Supplement
Semax
Peptide
Users say it helped54%helped384 reports · high confidence67%helped280 reports · high confidence
Verdict
Mixed
Mostly positive
ResearchBResearch: ModerateCResearch: Limited
Meta-analyses / RCTs1 / 130 / 1
Mainly used for
Focus
% reporting improvement
89% (199)90% (203)
Mood
% reporting improvement
39% (70)91% (74)
Memory
% reporting improvement
93% (72)96% (53)
Energy
% reporting improvement
84% (31)90% (68)
Anxiety
% reporting improvement
47% (15)84% (38)
Common side effectsdepression, headache, irritability, nauseahair loss, headache, tingling, mood swings
Typical dose reported100 mg / dailyNot listed
Alpha-Gpc
Latest review conclusion

α-GPC alone or in combination with donepezil improved cognition, behavior, and functional outcomes among patients with neurological conditions associated with cerebrovascular injury.

J Alzheimers Dis, 2023 ↗
What a user said
“Since I started with L-Tyrosine and Alpha GPC each morning, 3-4 weeks ago. I don’t know which is more effective. But I now feel like I’m on ADHD meds. It’s been transformative.”
Full Alpha-Gpc profile →
Semax
What a user said
“The effects have been incredible. It feels like my background distractibility has just vanished. I can lock in and focus even when my phone and other distractions are right next to me.”
Full Semax profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate