Conclusion: Although HDS-drug interactions and contraindications primarily concerned a relatively small subset of commonly used medications and HDS entities, this review provides the summary to identify patients, HDS products, and medications that are more susceptible to HDS-drug interactions and contraindications. The findings would facilitate the health-care professionals to communicate these documented interactions and contraindications to their patients and/or caregivers thereby preventing serious adverse events and improving desired therapeutic outcomes.
Yohimbe side effects
Across 57 first-hand reports, people mentioned a side effect 23 times (about 40 per 100 reports). The most common: anxiety, nausea, heart racing. User reports show what people notice — they can't tell you whether Yohimbe is safe for you.
Reported side effects
anxiety8
nausea3
heart racing3
jitteriness2
insomnia2
sweating2
panic2
overstimulation1
What got worse for some people
In their own words
“one in particular nootropic WORKED LIKE MAD, It was Yohimbe...It gives an absolute terrifying adrenaline rush. I started to actually enjoy competition again.”
“ND doesn't have Yohimbe, and coincidentally(?) it's the only supplement that ever made me feel queasy within recommended doses.”
“Excellent pre-workout. Insane stimulant. Doesn't do much for mental benefits... Helps me move faster at work and in the gym. Worth every cent. Only bad experience is over-stimulation sometimes and slight mental shocks.”
“Yohimbe works pretty good too. I've experimented some with that. It's really tricky getting the dosage just right, IMO.”
“I’ve tried stuff like Yohimbe and Maca, and it gives me INSANE anxiety and a racing heartbeat”
“Yohimbe has worked wonders for my clients. Try 2.5mg of the HCI 2x a day”
Is Yohimbe safe? What the research covers
BResearch: Moderate3 meta-analyses · 3 randomized trials on PubMed
Int J Clin Pract · 2012
Evaluation of documented drug interactions and contraindications associated with herbs and dietary supplements: a systematic literature reviewObes Rev · 2005
Adverse events of herbal food supplements for body weight reduction: systematic reviewConclusion: Although the quality of the data does not justify definitive attribution of causality in most cases, the reported risks are sufficient to shift the risk-benefit balance against the use of most of the reviewed herbal weight-loss supplements. Exceptions are Garcinia cambogia and yerba mate, which merit further investigation.