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COQ10 side effects

Across 713 first-hand reports, people mentioned a side effect 8 times (about 1 per 100 reports). The most common: aggression, brain fog, skin rash. User reports show what people notice — they can't tell you whether COQ10 is safe for you.

Reported side effects

aggression1
brain fog1
skin rash1
stomach issues1
relaxation1
reduced stimulant1
disrupted sleep1
insomnia1

In their own words

“even the nootropics that some communities swear by did nothing for me (some that come to mind - racetams, tyrosine/NALT, NAC, methylated B vitamins...”
Didn't helpRead the discussion ↗
“regular supplementation of CoQ10 doesn't gel well with me. While it seems to help somewhat with energy levels, it also makes me somehow more mentally error prone.”
MixedRead the discussion ↗

Is COQ10 safe? What the research covers

AResearch: Strong176 meta-analyses · 405 randomized trials on PubMed
Clin Nutr · 2022
ESPEN micronutrient guideline

Conclusion: This guideline should enable addressing suboptimal and deficient status of a bundle of MNs in at-risk diseases. In particular, it offers practical advice on MN provision and monitoring during nutritional support.

Nutr Neurosci · 2023
Nutrition and bipolar disorder: a systematic review

Conclusion: Taken together, these preliminary findings suggest that dietetic approaches might be included as part of BD treatment. Also considering the high risk of metabolic disorders in individuals with BD, they should be encouraged to choose healthy dietary lifestyles, including daily intake of fruits, vegetables, seafood and whole grains.

COQ10 side effects: what 713 users report — PlainPill