People mainly take Yohimbe for energy, libido, anxiety. Based on 12 first-hand reports and 3 meta-analyses & systematic reviews in the medical literature. Ranked #536 of 1,974 overall.
Of reports that state an outcome, 44% are positive.
Of the people who reported each effect, the share who said it got better.
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
At least one meta-analysis, or 5+ randomized controlled trials. The grade measures how much human research exists — read the conclusions below for what it found.
Conclusion: The evidence for most dietary supplements as aids in reducing body weight is not convincing. None of the reviewed dietary supplements can be recommended for over-the-counter use.
PubMed 15051593 ↗Conclusion: Although HDS-drug interactions and contraindications primarily concerned a relatively small subset of commonly used medications and HDS entities, this review provides the summary to identify patients, HDS products, and medications that are more susceptible to HDS-drug interactions and contraindications. The findings would facilitate the health-care professionals to communicate these documented interactions and contraindications to their patients and/or caregivers thereby preventing serious adverse events and improving desired therapeutic outcomes.
PubMed 23067030 ↗Conclusion: Although the quality of the data does not justify definitive attribution of causality in most cases, the reported risks are sufficient to shift the risk-benefit balance against the use of most of the reviewed herbal weight-loss supplements. Exceptions are Garcinia cambogia and yerba mate, which merit further investigation.
PubMed 15836459 ↗As stated by users — not a recommendation. Follow the label or your doctor.
How often each side effect came up across all reports.
Verbatim quotes, shortened only — each links to the original discussion.
“....TIL don't combine yohimbe and modfinil. check.”
“none of those over-the-counter products worked anything like Yohimbine HCL”
“Excellent pre-workout. Insane stimulant. Doesn't do much for mental benefits... Helps me move faster at work and in the gym. Worth every cent. Only bad experience is over-stimulation sometimes and slight mental shocks.”
“Yohimbe works pretty good too. I've experimented some with that. It's really tricky getting the dosage just right, IMO.”
“Most likely. Stimulants cause anxiety. Unless the pre-workout you are taking has other stimulants in it like Yohimbe, Ephedrine, or Theobromine.”
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate