SSRI/Snri
The short answer. There isn't much data on SSRI/Snri yet — 4 mentions, 4 with a clear outcome — so treat these numbers as anecdotal.
What users report
25%helped4 reports · few reports
1 helped0 mixed3 didn't help
From 4 mentions in total — the rest didn't say how it went and aren't counted.
Clinical research
Not graded
What SSRI/Snri does, according to users
Of the people who reported each effect, the share who said it got better.
betterno changeworse
What the research says
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
Research data for SSRI/Snri is being compiled.
Dosage people report
We don't list doses for prescription medications. Dosing should only come from a doctor or pharmacist.
Reported side effects
How often each side effect came up across all reports.
nose bleeds ×1insomnia ×1depersonalization ×1memory problems ×1psychotic ×1
What users say
First-hand experiences, quoted verbatim. We show one positive and one negative where both exist.
“I have found the SSRI/SNRI class of medication to be quite helpful against anxiety.”
“I've been on every SSRI in the book. Even SNRIs. All of them made me worse throughout a 3 year trial.”
“I've tried several "depression medications" such as zoloft, cymbalta, and prozac and they only make it worse. Much, much worse.”
“The anti-depressants gave me nose bleeds, insomnia (with some), depersonalization, memory problems, and with some I would become psychotic.”
Top discussions (4)
Other options for anxiety
Lithium Orotate
Supplement
AResearch: Strong
Selank
Peptide
CResearch: Limited
L-Theanine
Supplement
AResearch: Strong
Skullcap
Supplement
BResearch: Moderate
Taurine
Supplement
AResearch: Strong
Kava
Supplement
AResearch: Strong
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 3, 2026. How we rate