Spironolactone
People mainly take Spironolactone for skin & hair, hormones, focus. Based on 2 first-hand reports. Ranked #1347 of 1,974 overall.
14
User score
Mixed50% positive50% mixed0% negative0% unclear
Of reports that state an outcome, 50% are positive.
Clinical research
Research pending
What Spironolactone does, according to users
Of the people who reported each effect, the share who said it got better.
betterno changeworse
What the research says
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
Research data for Spironolactone is being compiled.
Dosage people report
As stated by users — not a recommendation. Follow the label or your doctor.
dailyas reported
Reported side effects
How often each side effect came up across all reports.
brain fog ×1fatigue ×1
What users say
Verbatim quotes, shortened only — each links to the original discussion.
“The first month or so while my T levels dropped I definitely had a 'brain fog' and constantly felt tired. After that first month I don't notice a massive difference cognitively”
“I have to stop taking Spironolactone soon and I am terrified to come off of it (hirsutism/acne/scalp hair loss).”
Top discussions (2)
- Loss of brain omega-3 transporters causes blood-brain barrier leakage; roughly half of all forms of dementia start with this - which predicts cognitive decline and could rival amyloid-beta in its overall importance in dementia. Can we stop the leaks? Rhonda Patrick interviews Dr. Axel Montagne. ↗
- What are the neurological effects of Testosterone? ↗
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User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate