Semaglutide reviews: what real users say
We read 330 first-hand mentions of Semaglutide from health and supplement communities. 228 of them say clearly how it went — and 64% of those say it helped.
Where people say it works: weight loss (85% of 138), appetite (80% of 70), blood sugar (90% of 10), performance (83% of 6).
Where it disappoints: energy (only 39% of 23 say better), mood (only 27% of 11 say better), digestion (only 43% of 7 say better).
Most common complaints: nausea, fatigue, stomach issues, constipation, vomiting. All side effects →
Positive experiences
“I've lost 35lbs since then and now I'm in the Healthy range on BMI. My IBSD has virtually disappeared.”
“Other things I take are semiglutide and TRT... recently made some major life changes and lost 80 pounds.”
“I know people taking sem for alcohol cessation and gambling addictions. It works for both. Better than anything else for alcoholism, it seems to be a miracle drug for alcoholics.”
“Started working right away. First day I didn't eat for 8 hours and I only did because I knew I needed to.”
“I was thicker than you, but not obese... Worked great as a cutting agent.”
“I got semaglutide from peptide sciences. It worked - I got appetite suppression and dropped weight.”
Negative and mixed experiences
“I tried ozempic at first. Made me really sick so I stopped.”
“I recently cycled off Ozempic after 6 months. It did not agree with me...profund depression...profound depression(something I dont normally have an issue with).”
“I’ve noticed since getting on the wegovy I have felt like I’ve been in a strange depression. I’m not explicitly suicidal but I feel nothing - no happiness, no love, no hope.”
“I only take 300 mcg once per week and I notice a big difference.”
“With semaglutide, my side effects were fatigue, depression, and very mild nausea.”
“Worked for my husband, not for me. Made me nauseous and hungrier than normal.”
Quotes are verbatim and link to the original public discussion. Information only — not medical advice. How we collect reports