Yes, for most people. 85% of 138 people who reported on Semaglutide for weight loss say it improved. 12% noticed no change and 4% say it got worse. That is below the typical result for weight loss (91% across 22 options).
Ranked #13 of 22 for weight loss.
“I've lost 35lbs since then and now I'm in the Healthy range on BMI. My IBSD has virtually disappeared.”
“Other things I take are semiglutide and TRT... recently made some major life changes and lost 80 pounds.”
“I know people taking sem for alcohol cessation and gambling addictions. It works for both. Better than anything else for alcoholism, it seems to be a miracle drug for alcoholics.”
“I only take 300 mcg once per week and I notice a big difference.”
Conclusion: This study shows that new anti-diabetic drugs, particularly GLP1-RA and Tirzepatide, are the most effective in inducing weight loss in patients with type 2 diabetes. Interestingly, exenatide appears to be the only GLP1-RA that induces a mild weight loss.
Conclusion: Among individuals with obesity without type 2 diabetes, subcutaneous semaglutide is effective for weight loss with an 11.85% reduction from baseline compared to placebo. This supports the use of semaglutide for weight management in obesity. However, risk of gastrointestinal adverse events, discontinuation of treatment and serious adverse events were higher in the semaglutide group versus placebo.
Conclusion: Potent GLP-1 RAs, such as tirzepatide and semaglutide, demonstrate greater overall weight loss but are associated with a significant reduction in lean mass.
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