Across 220 first-hand reports, people mentioned a side effect 9 times (about 4 per 100 reports). The most common: low mood, stomach upset, vertigo. User reports show what people notice — they can't tell you whether Reishi is safe for you.
“Reishi is good too (at night), plus cordyceps and maitake. That stuff really helped me get functioning again.”
“In the past I have taken lions mane and reishi daily, which actually worked well. I stopped because of the possible negative effects on testosterone and libido.”
“Red reshi puts me to sleep. But it is a potent DHT inhibitor so I only use it sometimes. It makes for great sleep though.”
“The only effects I've felt from any of these is either very mild energy or mood stabilization”
“I started taking it a few weeks ago and can't say I've noticed any specific effects”
Conclusion: Evidence from a small number of randomised controlled trials does not support the use of G lucidum for treatment of cardiovascular risk factors in people with type 2 diabetes mellitus. Future research into the efficacy of G lucidum should be placebo-controlled and adhere to clinical trial reporting standards.
Conclusion: Therefore, this review summarizes the current knowledge on G. lucidum or its individual components in relation to chemotherapeutic efficacy, ability to reverse multidrug resistance, and chemotherapeutic toxicity.