Conclusion: In conclusion, dysrhythmias are frequent in SSc cohorts. Paraclinical and laboratory parameters are useful instruments that could lead to early diagnosis in the course of the disease.
PubMed 36361752 ↗Prohormones
The short answer. There isn't much data on Prohormones yet — 8 mentions, 5 with a clear outcome — so treat these numbers as anecdotal. There is a moderate body of research — 1 meta-analyses and 4 trials.
From 8 mentions in total — the rest didn't say how it went and aren't counted.
What Prohormones does, according to users
Of the people who reported each effect, the share who said it got better.
What the research says
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
At least one meta-analysis, or 5+ randomized controlled trials. The grade measures how much human research exists — read the conclusions below for what it found.
Dosage people report
As stated by users — not a recommendation. Follow the label or your doctor.
Reported side effects
How often each side effect came up across all reports.
What users say
First-hand experiences, quoted verbatim. We show one positive and one negative where both exist.
“my sperm colour changed and produced less sperm almost straight away”
“Some people would say pro hormones but I wouldn’t mess with that stuff as it can have real side affects.”
Top discussions (5)
Other options for performance
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 3, 2026. How we rate