PlainPill

Natural Calm

People mainly take Natural Calm for sleep, anxiety. Based on 8 first-hand reports and 5 meta-analyses & systematic reviews in the medical literature. Ranked #275 of 3,539 overall.

42
User score
Mostly positive
62% positive0% mixed12% negative25% unclear

Of reports that state an outcome, 84% are positive.

Clinical research
BModerate research base
5
meta-analyses
0
RCTs
0
papers

What Natural Calm does, according to users

Of the people who reported each effect, the share who said it got better.

1 more with fewer than 3 reports
betterno changeworse

What the research says

Systematic reviews and meta-analyses from PubMed, with their published conclusions.

BModerate research base

At least one meta-analysis, or 5+ randomized controlled trials. The grade measures how much human research exists — read the conclusions below for what it found.

Alcohol Alcohol · 2009 · Meta-analysis / systematic review
The Korsakoff syndrome: clinical aspects, psychology and treatment

Conclusion: Although we now have substantial knowledge about the nature of this disorder, scientific questions (e.g. regarding the underlying genetics) remain. More particularly, there is a dearth of appropriate long-term care facilities for these patients, given that empirical research has shown that good practice has beneficial effects.

PubMed 19151162 ↗
Syst Rev · 2018 · Meta-analysis / systematic review
Using tocolysis in pregnant women with symptomatic placenta praevia does not significantly improve prenatal, perinatal, neonatal and maternal outcomes: a systematic review and meta-analysis

Conclusion: In women with symptomatic placenta praevia, there is no significant effect on pregnancy prolongation with the use of tocolysis. Tocolysis has no significant effect on other prenatal, perinatal, neonatal and maternal outcomes among women with symptomatic placenta praevia.

PubMed 30591076 ↗

Dosage people report

As stated by users — not a recommendation. Follow the label or your doctor.

2 teaspoonsbefore bed each night

Reported side effects

How often each side effect came up across all reports.

No side effects reported so far.

What users say

First-hand experiences, quoted verbatim. We show one positive and one negative where both exist.

Other options for sleep

User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 3, 2026. How we rate