Lithium vs Lithium Orotate for mood
Short answer: For mood, more users report improvement with Lithium Orotate — 91% of 70 reports, versus 73% of 11 for Lithium.
Lithium has 581 meta-analyses and 979 randomized trials on PubMed; Lithium Orotate has 0 and 0.
Based on 50 reports about Lithium and 220 about Lithium Orotate. Not medical advice.
| Lithium Medication | Lithium Orotate Supplement | |
|---|---|---|
| User score | 31 | 54 |
| Verdict | Mixed | Mostly positive |
| Positive of reports that state an outcome | 53% | 75% |
| Reports | 50 | 220 |
| Research | AResearch: Strong | DResearch: None |
| Meta-analyses / RCTs | 581 / 979 | 0 / 0 |
| Mainly used for | ||
| Focus % reporting improvement | 50% (2) | 77% (13) |
| Energy % reporting improvement | — | 100% (3) |
| Sleep % reporting improvement | — | 100% (15) |
| Anxiety % reporting improvement | 67% (3) | 97% (58) |
| Mood % reporting improvement | 73% (11) | 91% (70) |
| Memory % reporting improvement | — | 100% (2) |
| Common side effects | brain fog, tremors, rls, neck twitching | brain fog, drowsiness, diarrhea, emotional blunting |
| Typical dose reported | low dose | 1-2 tablets |
Although it is yet to be determined which is more effective between lithium or lecanemab or donanemab, lithium may be more effective than aducanumab. Aducanumab, lecanemab and donanemab do not appear to differ in their effectiveness on cognitive function. Low-dose lithium may be safer than aducanumab, lecanemab and donanemab.
Ageing Res Rev, 2024 ↗“I no longer need to take lithium for my bipolar disorder”
“Why not lithium instead? ... Bioavailability of lithium orotate is high, effective dose is very small. Proven to also modualte mood”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate