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Lithium Orotate side effects

Across 307 first-hand reports, people mentioned a side effect 14 times (about 5 per 100 reports). The most common: brain fog, emotional blunting, sexual dysfunction. User reports show what people notice — they can't tell you whether Lithium Orotate is safe for you.

Reported side effects

brain fog3
emotional blunting2
sexual dysfunction2
drowsiness2
diarrhea2
difficulty waking1
kidney damage1
thyroid interference1

What got worse for some people

Mood6% worse · 92% better · of 108

In their own words

“The lithium is absolutely curbing my mania... My social anxiety is 100% gone when I take lithium orotate.”
HelpedRead the discussion ↗
“Been taking 10-20 mg for a week or so... my mood is more stable. Rumination is not really there... Highly recommend... Ended up getting sexual dysfunction from it, stopped it.”
MixedRead the discussion ↗
“I take 5mg LiOr every morning upon waking for ADHD, and I've experienced nothing but massive benefits...Many people complain about lethargy and brain fog at these doses.”
MixedRead the discussion ↗
“Feel amazing on it - relaxed, sociable, motivated, sense of well-being and purpose... I’m on 2.5mg lithium orotate, twice per day.”
MixedRead the discussion ↗
“Lithium Orotate helped me a lot with brain fog and social interaction. It's extremely calming...However, it did seem to flatten my emotions a bit.”
MixedRead the discussion ↗

Is Lithium Orotate safe? What the research covers

AResearch: Strong581 meta-analyses · 979 randomized trials on PubMed
Ageing Res Rev · 2024
Comparative efficacy, tolerability and acceptability of donanemab, lecanemab, aducanumab and lithium on cognitive function in mild cognitive impairment and Alzheimer's disease: A systematic review and network meta-analysis

Conclusion: Although it is yet to be determined which is more effective between lithium or lecanemab or donanemab, lithium may be more effective than aducanumab. Aducanumab, lecanemab and donanemab do not appear to differ in their effectiveness on cognitive function. Low-dose lithium may be safer than aducanumab, lecanemab and donanemab.

Lithium Orotate side effects: what 307 users report — PlainPill