Lisdexamphetamine
People mainly take Lisdexamphetamine for energy. Based on 10 first-hand reports. Ranked #2560 of 3,539 overall.
11
User score
Mixed0% positive40% mixed10% negative50% unclear
Of reports that state an outcome, 0% are positive.
Clinical research
Research pending
What Lisdexamphetamine does, according to users
Of the people who reported each effect, the share who said it got better.
6 more with fewer than 3 reports
betterno changeworse
What the research says
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
Research data for Lisdexamphetamine is being compiled.
Dosage people report
As stated by users — not a recommendation. Follow the label or your doctor.
up to 10-15 mg/day in divided doses2 days/week for about a year
30 mgAM
20-23 mg (approximately 7-9 mg d-amphetamine equivalent)Sunday-Thursday, 5 days per week with 2-day breaks
50 mgas reported
100 mgas reported
low dosesas reported
Reported side effects
How often each side effect came up across all reports.
fatigue ×1weakness ×1adrenal insufficiency ×1sweating ×1jaw clench ×1physical tightness ×1burnout ×1apathy during ×1
What users say
First-hand experiences, quoted verbatim. We show one positive and one negative where both exist.
“I felt the added LSD helped apply different things I knew to the problem...but unfortunately, as time went on that week, I felt that I was not productive without the aid of the drugs.”
“Vyvanse has me geeked for 10-12 hours and after a nights sleep, I get a glow effect like it's still active when I wake up.”
“2 days of a therapeutic dose per week of amphetamine gave me a functional adrenal insufficiency.”
“I don't want to take them every day though, because they affect my identity and creativity.”
Top discussions (5)
- Rate my routine ↗
- What are some opinions on the once a week use of adderall in terms of tolerance, addiction, receptor downregulation, effect on baseline dopamine levels, etc? ↗
- An unscientific but hopefully objective experience with taking small doses of amphetamines and microdosing LSD for short term cognitive enhancement. (wall of text) ↗
- Adderall alternatives in EU ↗
- There is no evidence that Vyvanse (lisdexamphetamine) is longer acting than IR dextroamphetamine. In fact, there is evidence to the contrary. ↗
Other options for energy
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MixedAResearch: Strong
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Caffeine
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Vitamin D
Supplement · 2,323 reports
87% report better energy
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Phenylpiracetam
Supplement · 649 reports
95% report better energy
Mostly positiveDResearch: None
Rhodiola
Supplement · 853 reports
86% report better energy
Mostly positiveAResearch: Strong
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 3, 2026. How we rate