PlainPill

IGF-1 Des

The short answer. There isn't much data on IGF-1 Des yet — 11 mentions, 5 with a clear outcome — so treat these numbers as anecdotal. We found no human trials on PubMed. It is not an approved supplement and carries real risks.

What users report
40%helped5 reports · few reports
2 helped3 mixed0 didn't help

From 11 mentions in total — the rest didn't say how it went and aren't counted.

Clinical research
DNo human trials found
0
meta-analyses
0
RCTs
6
papers
High-risk compound. Peptides are not approved as supplements, carry serious and sometimes irreversible risks, are banned in competitive sport and may be restricted where you live. Nothing here is a recommendation to use it.

What IGF-1 Des does, according to users

Of the people who reported each effect, the share who said it got better.

1 more with fewer than 3 reports
betterno changeworse

What the research says

Systematic reviews and meta-analyses from PubMed, with their published conclusions.

DNo human trials found

No randomized controlled trials in humans found on PubMed. The grade measures how much human research exists — read the conclusions below for what it found.

No meta-analyses or systematic reviews published yet — 0 randomized trials found.

Dosage people report

We don't list doses for unapproved research compounds. Dosing should only come from a doctor or pharmacist.

Reported side effects

How often each side effect came up across all reports.

No side effects reported so far.

What users say

First-hand experiences, quoted verbatim. We show one positive and one negative where both exist.

“I ran IGF 1 DES intra muscular (pinned into muscle group to be worked out that day) at about 120mcg total combined dose”
HelpedRead the discussion ↗
“The first time I took IGF-DES yielded the most impressive results imaginable over 3 weeks, but they fell off”
MixedRead the discussion ↗
“My literal first pin of IGF1 DES gave me about a years worth of progress on my bench.”
HelpedRead the discussion ↗
Top discussions (5)

Other options for performance

User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 3, 2026. How we rate