Conclusion: This review highlighted several important cardiovascular impacts of e-cigarette use compared with non-use and cigarette smoking. However, the evidence is still limited and requires future research.
PubMed 40010935 ↗E-Cigarettes
The short answer. There isn't much data on E-Cigarettes yet — 7 mentions, 2 with a clear outcome — so treat these numbers as anecdotal. It is well studied — 264 meta-analyses on PubMed.
From 7 mentions in total — the rest didn't say how it went and aren't counted.
What E-Cigarettes does, according to users
Of the people who reported each effect, the share who said it got better.
What the research says
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
3+ meta-analyses or systematic reviews and 10+ randomized controlled trials in humans. The grade measures how much human research exists — read the conclusions below for what it found.
Conclusion: This study shows that both current and ever E-cigarette use have significant associations with asthma in adolescents. This knowledge might provide potential evidence for developing primary prevention strategies and serve as a reference for public health policy.
PubMed 35337694 ↗Conclusion: It provides crucial new knowledge about the efficacy of such interventions in preventing e-cigarette use and improving other outcomes (e.g., tobacco use, knowledge, intentions, attitudes, and mental health) among adolescents and the key characteristics associated with efficacious interventions. Our findings have important practical implications, highlighting future research directions for the development and evaluation of e-cigarette preventive interventions, along with the need to provide support to schools to help them identify and adopt evidence-based programs.
PubMed 39325296 ↗Conclusion: Based on the current analysis, conventional cigarette smoking is the most detrimental to periodontal health among the groups compared in all included studies. This indicates that traditional cigarettes have a more severe impact on periodontal tissues than do e-cigarettes. The data suggest a gradient of risk where nonsmokers have the lowest risk, e-cigarette users have a moderate risk, and cigarette smokers have the highest risk for periodontal health issues.
PubMed 39863518 ↗Dosage people report
As stated by users — not a recommendation. Follow the label or your doctor.
Reported side effects
How often each side effect came up across all reports.
What users say
First-hand experiences, quoted verbatim. We show one positive and one negative where both exist.
“Until it broke i was sucking on an e-cig all day and it helped my anxiety a lot.”
Top discussions (3)
- Nicotine may work for anxiety by blocking anxiety related receptors: “Nicotine acts like a key that unlocks nicotine receptors in the brain. Usually that key opens the receptor, but at other times nicotine is like a key that has gotten broken inside of the lock." ↗
- The influence of 8 and 16 mg nicotine patches on sleep in healthy non-smokers. (2014) ↗
- Carbonyl compounds in electronic cigarette vapors: effects of nicotine solvent and battery output voltage (2014) ↗
Other options for anxiety
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 3, 2026. How we rate