People mainly take Dioscorea for mood, libido. Based on 11 first-hand reports and 9 meta-analyses & systematic reviews in the medical literature. Ranked #1201 of 3,539 overall.
Of reports that state an outcome, 75% are positive.
Of the people who reported each effect, the share who said it got better.
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
3+ meta-analyses or systematic reviews and 10+ randomized controlled trials in humans. The grade measures how much human research exists — read the conclusions below for what it found.
Conclusion: DCs and DEs exhibit broad-spectrum anticancer properties. In particular, dioscin exhibits low toxicity and exerts strong anticancer effects through multiple pathways and targets. Future studies should focus on investigating these DEs and DCs, especially dioscin, as a novel anticancer agent.
PubMed 41033097 ↗Conclusion: A. membranaceus and R. Dioscoreae can significantly reduce UP production, and inhibition of UP wasn't time-dependent.
PubMed 37856796 ↗Conclusion: DnM exerts multi-target effects by modulating key inflammatory and apoptotic pathways in ADs. The NF-κB, STAT3, and TGF-β/Smad signaling pathways may serve as key targets for DnM in modulating inflammatory states in ADs, while Fas/FasL and Bax/Bcl-2 are potential mediators of its apoptosis-regulating effects. Clinical evidence supports its efficacy in rheumatoid arthritis (RA) and Hashimoto's thyroiditis (HT), highlighting its multi-faceted therapeutic potential. This review systematically summarizes DnM's clinical outcomes, mechanisms, and toxicological profile, however, large-scale randomize
PubMed 40633860 ↗Conclusion: Evidence from this review suggested that there appeared to be added clinical benefits associated with the use of Shanyao for DM, whether as a food supplement or as a CHM combined with hypoglycemic agents with a good safety profile.
PubMed 33244311 ↗As stated by users — not a recommendation. Follow the label or your doctor.
How often each side effect came up across all reports.
First-hand experiences, quoted verbatim. We show one positive and one negative where both exist.
“black ginger, horny goat weed, tribulus, dioscorea, cistamax, maca/black maca... they've all had crazy results when stacked in the bedroom for me”
“Tribulus and Dioscorea make me feel alpha in all the good and bad way, but recently unfortunately do cause some sort of bladder issue”
“Discorea did the dht and berb lowered my a1c”
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 3, 2026. How we rate