PlainPill

Chrysin

The short answer. There isn't much data on Chrysin yet — 8 mentions, 0 with a clear outcome — so treat these numbers as anecdotal. There is a moderate body of research — 8 meta-analyses and 5 trials.

What users report
0%helped0 reports · few reports
0 helped0 mixed0 didn't help

From 8 mentions in total — the rest didn't say how it went and aren't counted.

Clinical research
BModerate research base
8
meta-analyses
5
RCTs
2,275
papers

What Chrysin does, according to users

Of the people who reported each effect, the share who said it got better.

No specific effects reported yet.
betterno changeworse

What the research says

Systematic reviews and meta-analyses from PubMed, with their published conclusions.

BModerate research base

At least one meta-analysis, or 5+ randomized controlled trials. The grade measures how much human research exists — read the conclusions below for what it found.

J Ovarian Res · 2024 · Meta-analysis / systematic review
Efficacy of natural products on premature ovarian failure: a systematic review and meta-analysis of preclinical studies

Conclusion: Phytochemicals and marine natural product therapy (explicitly flavonoids, phenols, peptides, and alkaloids) has shown potential in enhancing folliculogenesis and improving ovarian function in animal models of POF. These findings provide promising strategies to protect ovarian reserve and reproductive health. Targeting oxidative stress and apoptosis pathways may be the underlying mechanism.

PubMed 38378652 ↗
Pharmacol Res · 2021 · Meta-analysis / systematic review
The antihypertensive potential of flavonoids from Chinese Herbal Medicine: A review

Conclusion: It is believed that more breakthrough studies are needed. Overall, this review may shed some new light on the explicit recognition of the mechanisms of anti-hypertension actions of flavonoids, pointing out the limitations of relevant research at the current stage and the aspects that should be strengthened in future researches.

PubMed 34601080 ↗
Naunyn Schmiedebergs Arch Pharmacol · 2025 · Meta-analysis / systematic review
Therapeutic potential of flavonoids in neuroprotection: brain and spinal cord injury focus

Conclusion: The full potential of flavonoids lies in their bioavailability, dose, and administration methods, but there are still challenges to overcome. This review explores flavonoid-induced neuroprotection, its clinical implications, future research opportunities, and molecular mechanisms, highlighting the potential for innovative CNS injury therapies and improved patient health outcomes.

PubMed 40014123 ↗
Curr Drug Targets · 2017 · Meta-analysis / systematic review
Recent Updates in Imperative Natural Compounds for Healthy Brain and Nerve Function: A Systematic Review of Implications for Multiple Sclerosis

Conclusion: Further studies with a focus on the molecular mechanisms of the protective natural compounds are needed to decrease possible side effects and to develop new medicines for MS. Apigenin, chrysin, baicalein, cyanidin, flavone glycoside, daidzein, coumestrol, sulforaphane, bee venom and huperzine A are the candidates for more prospective investigations.

PubMed 27829351 ↗

Dosage people report

As stated by users — not a recommendation. Follow the label or your doctor.

No doses stated in the reports so far.

Reported side effects

How often each side effect came up across all reports.

No side effects reported so far.

What users say

First-hand experiences, quoted verbatim. We show one positive and one negative where both exist.

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User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 3, 2026. How we rate