Conclusion: Conclusions: This is the first meta-analysis specifically focused on aerobic time-trial performance to suggest that pre-exercise ingestion of low caffeine doses (1.3-3 mg·kg-1) may enhance endurance performance by reducing time-trial completion time. Notably, the use of moderate caffeine doses (4-6 mg·kg-1) appears to produce a more consistent ergogenic effect.
PubMed 42356375 ↗Anhydrous Caffeine
The short answer. There isn't much data on Anhydrous Caffeine yet — 3 mentions, 0 with a clear outcome — so treat these numbers as anecdotal. There is a moderate body of research — 1 meta-analyses and 25 trials.
From 3 mentions in total — the rest didn't say how it went and aren't counted.
What Anhydrous Caffeine does, according to users
Of the people who reported each effect, the share who said it got better.
What the research says
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
At least one meta-analysis, or 5+ randomized controlled trials. The grade measures how much human research exists — read the conclusions below for what it found.
Dosage people report
As stated by users — not a recommendation. Follow the label or your doctor.
Reported side effects
How often each side effect came up across all reports.
What users say
First-hand experiences, quoted verbatim. We show one positive and one negative where both exist.
More substances
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 3, 2026. How we rate