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Agmatine side effects

Across 790 first-hand reports, people mentioned a side effect 27 times (about 3 per 100 reports). The most common: drowsiness, vivid dreams, stomach issues. User reports show what people notice — they can't tell you whether Agmatine is safe for you.

Reported side effects

drowsiness7
vivid dreams6
stomach issues3
dizziness3
dissociation2
hallucinations2
anhedonia2
headache2

What got worse for some people

In their own words

“I usually take anywhere from 1.5g-3g nightly when going through a period of depression. I usually start feeling better almost immediately; within 1 or 2 days.”
MixedRead the discussion ↗
“Literally, within an hour of taking it I felt better than I have in many weeks.”
MixedRead the discussion ↗
“After taking it often for a few weeks, it stopped working and actually gave me really shitty sleep.”
MixedRead the discussion ↗
“the first dosage (1g) was fascinating in its uplifting, motivating power, followed by a massive hangover effect the next day...Every dosage since, it has actively made my day worse.”
MixedRead the discussion ↗
“My mood has been much more stable since I started taking agmatine a year ago. However, I also had a similar experience, feeling nauseous, sedated, and unmotivated.”
MixedRead the discussion ↗
“Agmatine can cause some drowsiness from my experience... If you are getting drowsy from the agmatine, dose it at night only, will still benefit from better sleep and to a lesser degree anxiety during the day.”
MixedRead the discussion ↗

Is Agmatine safe? What the research covers

BResearch: Moderate2 meta-analyses · 6 randomized trials on PubMed
J Alzheimers Dis · 2019
Discovery of Gut Bacteria Specific to Alzheimer's Associated Diseases is a Clue to Understanding Disease Etiology: Meta-Analysis of Population-Based Data on Human Gut Metagenomics and Metabolomics

Conclusion: Levels of food-derived monoamine oxidase inhibitors and anti-bacterial compounds, the potential modulators of ADAS-bacteria growth and biogenic amine production, were altered in C&A versus NNI. ADAS is attributable to potentially modifiable risk factors of AD associated diseases.

Agmatine side effects: what 790 users report — PlainPill