PlainPill

Adrafinil

People mainly take Adrafinil for focus, energy, mood. Based on 93 first-hand reports and 0 meta-analyses & systematic reviews in the medical literature. Ranked #162 of 1,974 overall.

45
User score
Mixed
15% positive8% mixed17% negative60% unclear

Of reports that state an outcome, 38% are positive.

Clinical research
DNo human trials found
0
meta-analyses
0
RCTs
36
papers

What Adrafinil does, according to users

Of the people who reported each effect, the share who said it got better.

What the research says

Systematic reviews and meta-analyses from PubMed, with their published conclusions.

DNo human trials found

No randomized controlled trials in humans found on PubMed. The grade measures how much human research exists — read the conclusions below for what it found.

No meta-analyses or systematic reviews published yet — 0 randomized trials found.

Dosage people report

As stated by users — not a recommendation. Follow the label or your doctor.

microdoseas reported
15 mgdaily
300+ mgevery other day and a weekend break
100-150 mgon occasion
900 mg-1.2 gas desired
5gdaily

Reported side effects

How often each side effect came up across all reports.

liver toxicity ×2insomnia ×2liver damage ×1aggression ×1disassociation ×1vivid dreams ×1mood changes ×1personality changes ×1

What users say

Verbatim quotes, shortened only — each links to the original discussion.

“Just buy adrafanil or find it yourself you dirty narc.”
Source discussion ↗
“The reason Adrafinil was never adopted was the guaranteed liver damage.”
Source discussion ↗
“I microdose adrafanil and have adhd and it actually controls what I say and make it less likely for me to embarass myself”
Source discussion ↗
“Adrafinil has weaker effect, but worse side effects.”
Source discussion ↗
“and some Adrafinil because I couldn't find a doc to give me provigil.”
Source discussion ↗
Top discussions (5)

Other options for focus

User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate