Adrafinil vs Caffeine for focus
Short answer: For focus, users rate them about the same: 83% report improvement with Adrafinil (100 reports) and 83% with Caffeine (568 reports).
Adrafinil has 0 meta-analyses and 0 randomized trials on PubMed; Caffeine has 680 and 2,072.
Based on 399 reports about Adrafinil and 2,414 about Caffeine. Not medical advice.
| Adrafinil Medication | Caffeine Substance | |
|---|---|---|
| Users say it helped | 49%helped172 reports · high confidence | 47%helped1,448 reports · high confidence |
| Verdict | Mixed | Mixed |
| Research | DResearch: None | AResearch: Strong |
| Meta-analyses / RCTs | 0 / 0 | 680 / 2,072 |
| Mainly used for | ||
| Energy % reporting improvement | 87% (93) | 83% (908) |
| Focus % reporting improvement | 83% (100) | 83% (568) |
| Anxiety % reporting improvement | 57% (7) | 16% (240) |
| Mood % reporting improvement | 79% (14) | 74% (137) |
| Sleep % reporting improvement | 0% (6) | 15% (131) |
| Common side effects | liver stress, insomnia, liver damage, anxiety | jitteriness, anxiety, insomnia, headache |
| Typical dose reported | Not listed | 100-150 mg / daily |
“I take 300mg Adrafinil as soon as I get up, and usually in 90 minutes I can feel its effects. I don't get any high, no peak, no plateau and no crash.”
To avoid reductions in total sleep time, coffee (107 mg per 250 mL) should be consumed at least 8.8 h prior to bedtime and a standard serve of pre-workout supplement (217.5 mg) should be consumed at least 13.2 h prior to bedtime. The results of the present study provide evidence-based guidance for the appropriate consumption of caffeine to mitigate the deleterious effects on sleep.
Sleep Med Rev, 2023 ↗“Personally, I feel and function much better if I keep my caffeine intake very low to zero.”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate