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Caffeine, nicotine, alcohol and other everyday psychoactive substances. 144 rated.
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User score
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A–Z
Goal
Any
Weight loss
Appetite
Focus
Energy
Sleep
Anxiety
Mood
Memory
Performance
Recovery
Pain & inflammation
Digestion
Libido
Hormones
Heart & lipids
Skin & hair
Longevity
Research
Any
Moderate or strong
Strong only
15 results
1
54
LSD
Substance
Mood
Focus
Anxiety
100%
report better
Memory
2 reports
Mixed
A
Research: Strong
2
52
Caffeine
Substance
Energy
Focus
Anxiety
64%
report better
Memory
14 reports
Mixed
A
Research: Strong
3
50
Kratom
Substance
Mood
Anxiety
Energy
0%
report better
Memory
3 reports
Mixed
B
Research: Moderate
4
49
Phenibut
Substance
Anxiety
Mood
Sleep
33%
report better
Memory
3 reports
Mixed
B
Research: Moderate
5
46
Bromantane
Substance
Energy
Focus
Mood
100%
report better
Memory
3 reports
Mostly positive
B
Research: Moderate
6
46
Nicotine
Substance
Focus
Energy
Mood
69%
report better
Memory
13 reports
Mixed
A
Research: Strong
7
44
Psilocybin
Substance
Mood
Anxiety
Focus
100%
report better
Memory
7 reports
Mostly positive
A
Research: Strong
8
43
Nicotine Patch
Substance
Focus
Energy
Memory
100%
report better
Memory
2 reports
Mostly positive
A
Research: Strong
9
36
Cannabis
Substance
Sleep
Mood
Anxiety
0%
report better
Memory
5 reports
Mixed
A
Research: Strong
10
34
Nicotine Gum
Substance
Focus
Energy
Anxiety
67%
report better
Memory
3 reports
Mixed
A
Research: Strong
11
31
Methylene Blue
Substance
Energy
Focus
Mood
100%
report better
Memory
2 reports
Mostly positive
A
Research: Strong
12
25
THC
Substance
Anxiety
Sleep
Memory
0%
report better
Memory
6 reports
Mixed
A
Research: Strong
13
23
Marijuana
Substance
Sleep
Focus
Memory
25%
report better
Memory
4 reports
Mixed
A
Research: Strong
14
23
MDMA
Substance
Mood
Anxiety
Memory
0%
report better
Memory
4 reports
Mixed
A
Research: Strong
15
19
Ibogaine
Substance
Memory
Recovery
100%
report better
Memory
2 reports
Mostly positive
B
Research: Moderate
Best substances — ranked by user results & research — PlainPill