Vitamin K2 vs Vitamin K2 MK4 for heart & lipids
Short answer: For heart & lipids, more users report improvement with Vitamin K2 — 91% of 23 reports, versus 50% of 2 for Vitamin K2 MK4.
Vitamin K2 has 36 meta-analyses and 99 randomized trials on PubMed; Vitamin K2 MK4 has 0 and 0.
Based on 697 reports about Vitamin K2 and 29 about Vitamin K2 MK4. Not medical advice.
| Vitamin K2 Supplement | Vitamin K2 MK4 Supplement | |
|---|---|---|
| Users say it helped | 72%helped125 reports · high confidence | 62%helped10 reports · few reports |
| Verdict | Mostly positive | Mostly positive |
| Research | AResearch: Strong | DResearch: None |
| Meta-analyses / RCTs | 36 / 99 | 0 / 0 |
| Mainly used for | ||
| Heart & lipids % reporting improvement | 91% (23) | 50% (2) |
| Mood % reporting improvement | 93% (14) | — |
| Energy % reporting improvement | 100% (7) | 50% (2) |
| Sleep % reporting improvement | 60% (5) | — |
| Libido % reporting improvement | 80% (5) | — |
| Common side effects | heart palpitations, anxiety, palpitations, insomnia | fatigue, cold extremities, high blood, delayed reflexes |
| Typical dose reported | 75 mcg | 45 mg / daily |
The results of this meta-analysis seem to indicate that VK2 supplementation has a positive effect on the maintenance and improvement of BMD LS in postmenopausal women, and it can also reduce the fracture incidence, serum uc-OC levels and the ratio of uc-OC to cOC. In conclusion, VK2 can indirectly promote bone mineralization and increase bone strength.
Front Public Health, 2022 ↗“i believe k2, B vitamins, and amino acids L carnitine and glutamine made a difference in my skin.”
“I ran out of my K2 MK4 drops for the first time in a couple years since I've had long-covid and I started to feel extra worse after a couple weeks.”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate