PlainPill

Omega-3 vs Vitamin E for skin & hair

Short answer: For skin & hair, more users report improvement with Omega-3 — 90% of 48 reports, versus 80% of 5 for Vitamin E.

Omega-3 has 1,341 meta-analyses and 3,093 randomized trials on PubMed; Vitamin E has 680 and 1,761.

Based on 3,026 reports about Omega-3 and 212 about Vitamin E. Not medical advice.

Omega-3
Supplement
Vitamin E
Supplement
Users say it helped69%helped968 reports · high confidence47%helped36 reports · medium confidence
Verdict
Mostly positive
Mixed
ResearchAResearch: StrongAResearch: Strong
Meta-analyses / RCTs1,341 / 3,093680 / 1,761
Mainly used for
Mood
% reporting improvement
86% (289)—
Focus
% reporting improvement
85% (172)—
Pain & inflammation
% reporting improvement
93% (112)—
Heart & lipids
% reporting improvement
83% (108)100% (2)
Anxiety
% reporting improvement
74% (84)100% (2)
Common side effectsfish burps, stomach issues, vivid dreams, fishy burpscarcinogenic at, cancer risk, diarrhea, dizziness
Typical dose reported500/250 mg / daily400 mg
Omega-3
Latest review conclusion

For glycated hemoglobin, there was no significant effect in the meta-analysis. This systematic review with meta-analysis demonstrated that supplementation with omega-3 has protective effects on diabetes parameters.

Crit Rev Food Sci Nutr, 2022 ↗
What a user said
“I do supplement a lot of fish oil and vitamin A as retinyl palmitate though. It has really helped my depression, anxiety and ADHD and has enabled me to stop using more serious psychiatric drugs for those things.”
Full Omega-3 profile →
Vitamin E
Latest review conclusion

This study suggests the potential ability of vitamin C and E in alleviating pain symptoms experienced by individuals with endometriosis.

PLoS One, 2024 ↗
What a user said
“Vitamin E is the most effective supplement I've taken for anxiety, depression, lethargy, and anhedonia...even more effective than the SSRI.”
Full Vitamin E profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate