PlainPill

RAD-140 vs Tesamorelin for weight loss

Short answer: For weight loss, users rate them about the same: 93% report improvement with RAD-140 (61 reports) and 95% with Tesamorelin (82 reports).

RAD-140 has 0 meta-analyses and 0 randomized trials on PubMed; Tesamorelin has 3 and 21.

Based on 873 reports about RAD-140 and 265 about Tesamorelin. Not medical advice.

RAD-140
SARM
Tesamorelin
Peptide
Users say it helped42%helped541 reports · high confidence58%helped119 reports · high confidence
Verdict
Mixed
Mixed
ResearchDResearch: NoneAResearch: Strong
Meta-analyses / RCTs0 / 03 / 21
Mainly used for
Performance
% reporting improvement
93% (371)88% (25)
Weight loss
% reporting improvement
93% (61)95% (82)
Hormones
% reporting improvement
7% (76)100% (4)
Energy
% reporting improvement
44% (64)100% (5)
Mood
% reporting improvement
37% (63)—
Common side effectssuppression, hair loss, insomnia, fatiguewater retention, allergic reaction, anaphylaxis, swelling
Typical dose reportedNot listedNot listed
RAD-140
What a user said
“I did put on decent size and I feel a lot fuller. My strength and endurance has gone up tremendously. Side effects - Shedding of hair, anxiety...”
Full RAD-140 profile →
Tesamorelin
Latest review conclusion

However, limited data on long-term safety, optimal dosing strategies, and durability of treatment effects warrant caution. Future research should evaluate extended treatment duration, dose-response relationships, and patient-reported outcomes to establish comprehensive clinical utility.

J Int Assoc Provid AIDS Care, 2026 ↗
What a user said
“I also added Tesamorelin 2 months in due to the harder time sleeping on Retatrutide and wanting to accelerate the burn of my visceral fats (2mg 5x a week). Worked like magic for me.”
Full Tesamorelin profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate