Magnesium vs Tadalafil for heart & lipids
Short answer: For heart & lipids, users rate them about the same: 96% report improvement with Magnesium (26 reports) and 95% with Tadalafil (22 reports).
Magnesium has 82 meta-analyses and 210 randomized trials on PubMed; Tadalafil has 120 and 347.
Based on 2,391 reports about Magnesium and 253 about Tadalafil. Not medical advice.
| Magnesium Supplement | Tadalafil Medication | |
|---|---|---|
| Users say it helped | 73%helped956 reports · high confidence | 77%helped142 reports · high confidence |
| Verdict | Mostly positive | Mostly positive |
| Research | AResearch: Strong | AResearch: Strong |
| Meta-analyses / RCTs | 82 / 210 | 120 / 347 |
| Mainly used for | ||
| Sleep % reporting improvement | 88% (430) | 100% (4) |
| Anxiety % reporting improvement | 90% (289) | 75% (4) |
| Mood % reporting improvement | 82% (118) | 100% (10) |
| Libido % reporting improvement | 67% (15) | 91% (99) |
| Energy % reporting improvement | 75% (83) | 100% (6) |
| Common side effects | diarrhea, drowsiness, stomach issues, vivid dreams | headache, stuffy nose, heartburn, lower back |
| Typical dose reported | 500 mg / daily | Not listed |
This review confirms that the quality of literature is substandard for physicians to make well-informed recommendations on usage of oral magnesium for older adults with insomnia. However, given that oral magnesium is very cheap and widely available, RCT evidence may support oral magnesium supplements (less than 1 g quantities given up to three times a day) for insomnia symptoms.
BMC Complement Med Ther, 2021 ↗“after supplementing with 400mg of Magnesium daily. Winter blues hit me hard and my multivitamin wasn't doing any justice, but once I began supplementing Magnesium, everything changed.”
Tadalafil shares a similar efficacy and safety with sildenafil and significantly improves patients' sexual confidence. Furthermore, patients and their partners prefer tadalafil to sildenafil. Hence, tadalafil may be a better choice for ED treatment.
Int Urol Nephrol, 2017 ↗“After a week of 2.5 mg twice a day, this is my favourite drug ever. My brain fog has gone...My mood is so much better, similar to an SSRI but without the flat feeling.”
Related comparisons
Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate