PlainPill

Glutamine vs L-Glutamine for digestion

Short answer: For digestion, more users report improvement with Glutamine — 100% of 11 reports, versus 92% of 26 for L-Glutamine.

Glutamine has 361 meta-analyses and 787 randomized trials on PubMed; L-Glutamine has 19 and 117.

Based on 146 reports about Glutamine and 141 about L-Glutamine. Not medical advice.

Glutamine
Supplement
L-Glutamine
Supplement
Users say it helped37%helped55 reports · medium confidence60%helped59 reports · medium confidence
Verdict
Mixed
Mixed
ResearchAResearch: StrongAResearch: Strong
Meta-analyses / RCTs361 / 78719 / 117
Mainly used for
Digestion
% reporting improvement
100% (11)92% (26)
Mood
% reporting improvement
67% (3)88% (17)
Recovery
% reporting improvement
100% (11)78% (9)
Anxiety
% reporting improvement
100% (4)71% (14)
Energy
% reporting improvement
100% (4)83% (6)
Common side effectsurine odor, headache, vivid dreams, stomach issuesstomach issues, anxiety, weird feeling, glutamate spikes
Typical dose reported5 mg / before bed5 g
Glutamine
Latest review conclusion

In studies using high-throughput metabolomics, several blood amino acids appear to be consistently associated with the risk of developing type 2 diabetes.

Diabetes Care, 2016 ↗
What a user said
“amino acids L carnitine and glutamine made a difference in my skin.”
Full Glutamine profile →
L-Glutamine
Latest review conclusion

Dentoxol mouthwashes, Plantago major extract, thyme honey extract, zinc oxide paste, vitamin B complex combined with GeneTime, and the consumption of L-glutamine are effective in diminishing the severity of OM. Pain intensity was lower with doxepin mouthwashes and diphenhydramine-lidocaine-antacid mouthwashes.

Acta Odontol Latinoam, 2023 ↗
What a user said
“I tried out L-glutamine. It worked! I saw some real results taking 15g a day.”
Full L-Glutamine profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate