PlainPill

L-Citrulline vs Taurine for heart & lipids

Short answer: For heart & lipids, users rate them about the same: 95% report improvement with L-Citrulline (22 reports) and 97% with Taurine (29 reports).

L-Citrulline has 14 meta-analyses and 101 randomized trials on PubMed; Taurine has 112 and 227.

Based on 231 reports about L-Citrulline and 1,053 about Taurine. Not medical advice.

L-Citrulline
Supplement
Taurine
Supplement
Users say it helped77%helped99 reports · medium confidence75%helped379 reports · high confidence
Verdict
Mostly positive
Mostly positive
ResearchAResearch: StrongAResearch: Strong
Meta-analyses / RCTs14 / 101112 / 227
Mainly used for
Anxiety
% reporting improvement
100% (2)93% (209)
Sleep
% reporting improvement
100% (2)92% (99)
Performance
% reporting improvement
98% (45)96% (26)
Energy
% reporting improvement
100% (11)90% (59)
Mood
% reporting improvement
100% (2)89% (57)
Common side effectscold sore, dizziness, headache, increased urinationdrowsiness, vivid dreams, headache, irritability
Typical dose reported8 g / 3x/week3-4 g
L-Citrulline
Latest review conclusion

Foods rich in polyphenols and nitrate provide trivial benefits for endurance exercise performance, although these effects may be food dependent. Highly trained endurance athletes do not appear to benefit from consuming nitrate-rich foods but may benefit from polyphenol consumption. Further research into food sources, dosage and supplementation duration to optimise the ergogenic response to polyphenol consumption is warranted. Further studies should evaluate whether differential sex-based responses to nitrate and polyphenol consumption are attributable to physiological differences or sample siz

J Int Soc Sports Nutr, 2021 ↗
What a user said
“Something I found that makes my meds work way better is Citrulline 2g + Arginine 2g twice daily.”
Full L-Citrulline profile →
Taurine
Latest review conclusion

Taurine showed noteworthy effects in preventing hypertension and enhancing cardiac function. Individuals prone to CVDs may find it advantageous to include taurine in their daily regimen.

Nutr J, 2024 ↗
What a user said
“it really is a smooth feeling. I had some music playing and actually enjoyed doing the dishes. It just put me in a very overall relaxed state.”
Full Taurine profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate