PlainPill

L-Citrulline vs Magnesium for heart & lipids

Short answer: For heart & lipids, users rate them about the same: 95% report improvement with L-Citrulline (22 reports) and 96% with Magnesium (26 reports).

L-Citrulline has 14 meta-analyses and 101 randomized trials on PubMed; Magnesium has 82 and 210.

Based on 231 reports about L-Citrulline and 2,391 about Magnesium. Not medical advice.

L-Citrulline
Supplement
Magnesium
Supplement
Users say it helped77%helped99 reports · medium confidence73%helped956 reports · high confidence
Verdict
Mostly positive
Mostly positive
ResearchAResearch: StrongAResearch: Strong
Meta-analyses / RCTs14 / 10182 / 210
Mainly used for
Sleep
% reporting improvement
100% (2)88% (430)
Anxiety
% reporting improvement
100% (2)90% (289)
Mood
% reporting improvement
100% (2)82% (118)
Energy
% reporting improvement
100% (11)75% (83)
Libido
% reporting improvement
98% (48)67% (15)
Common side effectscold sore, dizziness, headache, increased urinationdiarrhea, drowsiness, stomach issues, vivid dreams
Typical dose reported8 g / 3x/week500 mg / daily
L-Citrulline
Latest review conclusion

Foods rich in polyphenols and nitrate provide trivial benefits for endurance exercise performance, although these effects may be food dependent. Highly trained endurance athletes do not appear to benefit from consuming nitrate-rich foods but may benefit from polyphenol consumption. Further research into food sources, dosage and supplementation duration to optimise the ergogenic response to polyphenol consumption is warranted. Further studies should evaluate whether differential sex-based responses to nitrate and polyphenol consumption are attributable to physiological differences or sample siz

J Int Soc Sports Nutr, 2021 ↗
What a user said
“Something I found that makes my meds work way better is Citrulline 2g + Arginine 2g twice daily.”
Full L-Citrulline profile →
Magnesium
Latest review conclusion

This review confirms that the quality of literature is substandard for physicians to make well-informed recommendations on usage of oral magnesium for older adults with insomnia. However, given that oral magnesium is very cheap and widely available, RCT evidence may support oral magnesium supplements (less than 1 g quantities given up to three times a day) for insomnia symptoms.

BMC Complement Med Ther, 2021 ↗
What a user said
“after supplementing with 400mg of Magnesium daily. Winter blues hit me hard and my multivitamin wasn't doing any justice, but once I began supplementing Magnesium, everything changed.”
Full Magnesium profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate