Glutamine vs Probiotics for digestion
Short answer: For digestion, more users report improvement with Glutamine — 100% of 11 reports, versus 84% of 86 for Probiotics.
Glutamine has 361 meta-analyses and 787 randomized trials on PubMed; Probiotics has 2,293 and 2,235.
Based on 146 reports about Glutamine and 479 about Probiotics. Not medical advice.
| Glutamine Supplement | Probiotics Supplement | |
|---|---|---|
| Users say it helped | 37%helped55 reports · medium confidence | 63%helped144 reports · high confidence |
| Verdict | Mixed | Mostly positive |
| Research | AResearch: Strong | AResearch: Strong |
| Meta-analyses / RCTs | 361 / 787 | 2,293 / 2,235 |
| Mainly used for | ||
| Digestion % reporting improvement | 100% (11) | 84% (86) |
| Mood % reporting improvement | 67% (3) | 100% (54) |
| Anxiety % reporting improvement | 100% (4) | 90% (29) |
| Energy % reporting improvement | 100% (4) | 80% (10) |
| Focus % reporting improvement | 100% (2) | 70% (10) |
| Common side effects | urine odor, headache, vivid dreams, stomach issues | stomach issues, brain fog, diarrhea, withdrawal |
| Typical dose reported | 5 mg / before bed | 2 capsules / daily |
In studies using high-throughput metabolomics, several blood amino acids appear to be consistently associated with the risk of developing type 2 diabetes.
Diabetes Care, 2016 ↗“amino acids L carnitine and glutamine made a difference in my skin.”
Some combinations of probiotics or strains may be beneficial in IBS. However, certainty in the evidence for efficacy by GRADE criteria was low to very low across almost all of our analyses.
Gastroenterology, 2023 ↗“What finally made a difference was taking probiotics...I felt better fairly quickly.”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate