GHK-Cu vs NMN for skin & hair
Short answer: For skin & hair, more users report improvement with NMN — 100% of 14 reports, versus 87% of 202 for GHK-Cu.
GHK-Cu has 0 meta-analyses and 1 randomized trials on PubMed; NMN has 11 and 17.
Based on 496 reports about GHK-Cu and 366 about NMN. Not medical advice.
| GHK-Cu Peptide | NMN Supplement | |
|---|---|---|
| Users say it helped | 62%helped223 reports · high confidence | 61%helped113 reports · high confidence |
| Verdict | Mostly positive | Mostly positive |
| Research | CResearch: Limited | AResearch: Strong |
| Meta-analyses / RCTs | 0 / 1 | 11 / 17 |
| Mainly used for | ||
| Skin & hair % reporting improvement | 87% (202) | 100% (14) |
| Energy % reporting improvement | — | 92% (77) |
| Pain & inflammation % reporting improvement | 90% (31) | 83% (6) |
| Recovery % reporting improvement | 96% (27) | 100% (5) |
| Sleep % reporting improvement | 80% (5) | 65% (20) |
| Common side effects | injection site, redness, stinging, injection pain | insomnia, jitteriness, drowsiness, elevated blood |
| Typical dose reported | Not listed | 1 g / daily |
GHK-CuFull GHK-Cu profile →
What a user said
“Love it. 44 F. Totally helped even out my skin tone (Irish red cheeks), reduced wrinkles on my forehead and neck, thickened my hair which had been thinning, and grew my eye lashes.”
NMNFull NMN profile →
Latest review conclusion
Overall, NAD⁺ augmentation shows clear biological activity, but clinical effectiveness for anti-aging or wellness outcomes remains inconclusive. Larger, well-designed randomized trials with longer follow-up and prespecified clinically meaningful endpoints are needed, particularly for parenteral approaches.
Ageing Res Rev, 2026 ↗What a user said
“I've been using NMN for 3 years now, and I had great results with it along with many other supplements. I'm 47 and I look a lot younger and healthier than when I first started NMN.”
Related comparisons
Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate