PlainPill

Citrulline vs Taurine for heart & lipids

Short answer: For heart & lipids, users rate them about the same: 100% report improvement with Citrulline (14 reports) and 97% with Taurine (29 reports).

Citrulline has 51 meta-analyses and 258 randomized trials on PubMed; Taurine has 112 and 227.

Based on 157 reports about Citrulline and 1,053 about Taurine. Not medical advice.

Citrulline
Supplement
Taurine
Supplement
Users say it helped84%helped58 reports · medium confidence75%helped379 reports · high confidence
Verdict
Mostly positive
Mostly positive
ResearchAResearch: StrongAResearch: Strong
Meta-analyses / RCTs51 / 258112 / 227
Mainly used for
Anxiety
% reporting improvement
—93% (209)
Sleep
% reporting improvement
—92% (99)
Energy
% reporting improvement
75% (4)90% (59)
Mood
% reporting improvement
—89% (57)
Performance
% reporting improvement
100% (31)96% (26)
Common side effectserectile dysfunction, tooth erosion, tooth enamel, gerddrowsiness, vivid dreams, headache, irritability
Typical dose reported1 g3-4 g
Citrulline
Latest review conclusion

Supplementation of some but not all micronutrients may benefit cardiometabolic health. This study highlights the importance of micronutrient diversity and the balance of benefits and risks to promote and maintain cardiovascular health in diverse populations. (Antioxidant Supplementation in the Prevention and Treatment of Cardiovascular Diseases; CRD42022315165).

J Am Coll Cardiol, 2022 ↗
What a user said
“try all the standard vasodilators - citrulline and agmatine helped me a lot.”
Full Citrulline profile →
Taurine
Latest review conclusion

Taurine showed noteworthy effects in preventing hypertension and enhancing cardiac function. Individuals prone to CVDs may find it advantageous to include taurine in their daily regimen.

Nutr J, 2024 ↗
What a user said
“it really is a smooth feeling. I had some music playing and actually enjoyed doing the dishes. It just put me in a very overall relaxed state.”
Full Taurine profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate