PlainPill

Bromelain vs Quercetin for pain & inflammation

Short answer: For pain & inflammation, more users report improvement with Bromelain — 100% of 13 reports, versus 67% of 15 for Quercetin.

Bromelain has 34 meta-analyses and 53 randomized trials on PubMed; Quercetin has 207 and 232.

Based on 66 reports about Bromelain and 280 about Quercetin. Not medical advice.

Bromelain
Supplement
Quercetin
Supplement
Users say it helped82%helped11 reports · few reports58%helped67 reports · medium confidence
Verdict
Mostly positive
Mixed
ResearchAResearch: StrongAResearch: Strong
Meta-analyses / RCTs34 / 53207 / 232
Mainly used for
Pain & inflammation
% reporting improvement
100% (13)67% (15)
Immunity
% reporting improvement
—100% (15)
Energy
% reporting improvement
—100% (8)
Focus
% reporting improvement
—100% (7)
Sleep
% reporting improvement
—60% (5)
Common side effectsNone reportedinsomnia, jitteriness, anxiety, stimulation
Typical dose reported48 mg / daily500-1000 mg
Bromelain
Latest review conclusion

Conclusions: Moderate-quality studies demonstrated the potential of oral bromelain in pain control and topical bromelain in wound care. Major health risks were not reported during the treatment with bromelain.

Nutr Health, 2023 ↗
What a user said
“Quercetin and bromelain, Vitamin K and D, astaxanthan, fish oil, turmeric, boron, msm, and coq10. I have osteoarthritis and this combo has been helping with the pain.”
Full Bromelain profile →
Quercetin
Latest review conclusion

The results of a meta-analysis of 12 RCTs indicate that TCM intervention can improve the clinical treatment efficacy of CAG. NPAs identified seven hub TCM and 13 target genes associated with their actions, while bioinformatics analysis identified two DEGs between normal and CAG gastric tissues. Finally, molecular docking was employed to reveal the mechanism of action of the active molecules in TCM on the DEGs. These findings not only reveal the mechanisms of action of the active components of the TCMs, but also provide support for the development of new drugs, ultimately blocking the progressi

Ann Med, 2023 ↗
What a user said
“The above supplements have worked amazingly for my brain fog and motivation.”
Full Quercetin profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate