People mainly take Bromelain for sleep, energy, recovery. Based on 22 first-hand reports and 34 meta-analyses & systematic reviews in the medical literature. Ranked #769 of 1,974 overall.
Of reports that state an outcome, 100% are positive.
Of the people who reported each effect, the share who said it got better.
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
3+ meta-analyses or systematic reviews and 10+ randomized controlled trials in humans. The grade measures how much human research exists — read the conclusions below for what it found.
Conclusion: Conclusions: Moderate-quality studies demonstrated the potential of oral bromelain in pain control and topical bromelain in wound care. Major health risks were not reported during the treatment with bromelain.
PubMed 37157782 ↗Conclusion: Bromelain was first isolated and described in the late 19th century by researchers in Europe, who identified its proteolytic properties. Since then, bromelain has gained recognition in both traditional and modern medicine for its potential therapeutic effects.
PubMed 38999808 ↗Conclusion: The search was performed in PubMed, Science Direct, Scopus, Cochrane Library and Web of Science databases. Bromelain reduced IL-1β, IL-6 and TNF-α secretion when immune cells were already stimulated in an overproduction condition by proinflammatory cytokines, generating a modulation in the inflammatory response through prostaglandins reduction and activation of a cascade reactions that trigger neutrophils and macrophages, in addition to accelerating the healing process.
PubMed 38676413 ↗Conclusion: The general effect of bromelain supplementation on inflammation is inconsistent because of population heterogeneity, doses used, treatment duration, and parameters evaluated. The observed effects are punctual and isolated, and further standardization is needed to establish doses, supplementation time, and which type of inflammatory condition is indicated.
PubMed 37202035 ↗As stated by users — not a recommendation. Follow the label or your doctor.
How often each side effect came up across all reports.
Verbatim quotes, shortened only — each links to the original discussion.
“I am taking: Omega 3, Ribes nigrum, Lions mane, Bromeline, Ginger extract, Msm”
“Quercetin Vitamin C and Bromelain(QCB) covid-19 prophylaxis study”
“Some people with long covid have had success with Bromelaine and NAC.”
“cutting out histamine-lowering supplements like Reishi, Quercetin and Bromelain”
“Bromelain and N-acetylcysteine significantly inhibited cell proliferation, more potently in combination therapy.”
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate