Bromantane vs Tianeptine for mood
Short answer: For mood, users rate them about the same: 95% report improvement with Bromantane (74 reports) and 95% with Tianeptine (148 reports).
Bromantane has 1 meta-analyses and 0 randomized trials on PubMed; Tianeptine has 18 and 42.
Based on 518 reports about Bromantane and 322 about Tianeptine. Not medical advice.
| Bromantane Supplement | Tianeptine Medication | |
|---|---|---|
| Users say it helped | 69%helped186 reports · high confidence | 63%helped155 reports · high confidence |
| Verdict | Mostly positive | Mostly positive |
| Research | BResearch: Moderate | AResearch: Strong |
| Meta-analyses / RCTs | 1 / 0 | 18 / 42 |
| Mainly used for | ||
| Mood % reporting improvement | 95% (74) | 95% (148) |
| Anxiety % reporting improvement | 96% (46) | 95% (62) |
| Energy % reporting improvement | 96% (90) | 86% (14) |
| Focus % reporting improvement | 89% (70) | 93% (14) |
| Performance % reporting improvement | 89% (9) | — |
| Common side effects | jitteriness, insomnia, headache, irritability | addiction, withdrawal, tolerance, headache |
| Typical dose reported | 130 mg / daily | Not listed |
The data from the meta-analysis showed that plant adaptogens could provide a number of benefits in the treatment of chronic fatigue, cognitive impairment, and immune protection. In the future, there is great potential to register medicinal products that contain plant adaptogens for therapeutic purposes.
Nutrients, 2021 ↗“Bromantane will reset dopamine baseline and stim tolerance but it also gives me crazy energy like a kid again.”
Compared to placebo, venlafaxine was associated with a lower incidence of dizziness, while desvenlafaxine, sertraline, and vortioxetine were associated with a higher incidence of nausea/vomiting. In conclusion, desvenlafaxine, paroxetine, venlafaxine, and vortioxetine had reasonable efficacy, acceptability, and tolerability in the treatment of adults with stable MDD.
Mol Psychiatry, 2023 ↗“It has really improved the quality of my life, more than anything else I have taken.”
Related comparisons
Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate