Boron vs Enclomiphene for hormones
Short answer: For hormones, users rate them about the same: 88% report improvement with Boron (51 reports) and 88% with Enclomiphene (96 reports).
Boron has 38 meta-analyses and 39 randomized trials on PubMed; Enclomiphene has 2 and 3.
Based on 394 reports about Boron and 373 about Enclomiphene. Not medical advice.
| Boron Supplement | Enclomiphene Medication | |
|---|---|---|
| User score | 31 | 45 |
| Verdict | Mostly positive | Mostly positive |
| Positive of reports that state an outcome | 71% | 61% |
| Reports | 394 | 373 |
| Research | AResearch: Strong | BResearch: Moderate |
| Meta-analyses / RCTs | 38 / 39 | 2 / 3 |
| Mainly used for | ||
| Weight loss % reporting improvement | 100% (2) | — |
| Focus % reporting improvement | 100% (3) | 50% (2) |
| Energy % reporting improvement | 100% (6) | 70% (10) |
| Sleep % reporting improvement | 100% (2) | 75% (4) |
| Anxiety % reporting improvement | 50% (2) | 0% (2) |
| Mood % reporting improvement | 64% (11) | 65% (17) |
| Performance % reporting improvement | 86% (7) | 33% (3) |
| Recovery % reporting improvement | 100% (3) | 100% (2) |
| Pain & inflammation % reporting improvement | 83% (6) | — |
| Libido % reporting improvement | 88% (49) | 71% (24) |
| Hormones % reporting improvement | 88% (51) | 88% (96) |
| Common side effects | irritability, depression, brain fog, hair loss | eye floaters, blurry vision, mood swings, fatigue |
| Typical dose reported | 10 mg / daily | 12.5 g daily (comment; likely mg) / daily for 2 months (comment) |
Regardless, some MTEs may possess the potential to improve athletic performance, but more high quality research is required before support for these MTEs can be given. PROSPERO preregistered (CRD42018090502).
Nutrients, 2019 ↗“No one has mentioned Boron and Zinc. They make a very noticeable difference for me.”
SERM therapy is associated with significantly improved levels of TT, LH, and FSH in hypogonadal men compared to placebo, and significantly enhanced levels of LH and FSH compared to T gel. The findings suggest that SERM therapy effectively increases TT levels in men with functional hypogonadism and should be considered as an alternative to T gel therapy.
Arch Endocrinol Metab, 2025 ↗“I second Enclomiphene citrate. Been on 12.5mg per day sublingual pill and my test went from 430 to 950. No side effects other than being more horny.”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate