PlainPill

Ashwagandha vs Saffron for mood

Short answer: For mood, more users report improvement with Saffron — 92% of 165 reports, versus 53% of 446 for Ashwagandha.

Ashwagandha has 48 meta-analyses and 59 randomized trials on PubMed; Saffron has 88 and 119.

Based on 2,447 reports about Ashwagandha and 421 about Saffron. Not medical advice.

Ashwagandha
Supplement
Saffron
Supplement
Users say it helped44%helped1,321 reports · high confidence62%helped223 reports · high confidence
Verdict
Mixed
Mostly positive
ResearchAResearch: StrongAResearch: Strong
Meta-analyses / RCTs48 / 5988 / 119
Mainly used for
Anxiety
% reporting improvement
88% (881)81% (84)
Mood
% reporting improvement
53% (446)92% (165)
Sleep
% reporting improvement
77% (233)72% (18)
Energy
% reporting improvement
53% (125)81% (21)
Libido
% reporting improvement
62% (127)74% (19)
Common side effectsanhedonia, drowsiness, fatigue, depressionheadache, appetite suppression, insomnia, vivid dreams
Typical dose reported800-1600 mg / after dinner30 mg
Ashwagandha
Latest review conclusion

The current systematic review and dose-response meta-analysis of RCTs revealed a beneficial effect in both stress and anxiety following Ashwagandha supplementation. However, further high-quality studies are needed to firmly establish the clinical efficacy of the plant.

Phytother Res, 2022 ↗
What a user said
“I paired it with maca and ashwaganda and it legit felt like a steroid cycle.”
Full Ashwagandha profile →
Saffron
Latest review conclusion

Saffron demonstrates promise in improving ADHD symptoms, with an acceptable safety profile. Future well-designed multicentral studies are suggested.

J Atten Disord, 2024 ↗
What a user said
“I just sneak some into whatever soup we are having. I honestly think it has made a huge difference.”
Full Saffron profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate