PlainPill

Ashwagandha vs L-Tryptophan for sleep

Short answer: For sleep, more users report improvement with L-Tryptophan — 89% of 54 reports, versus 77% of 233 for Ashwagandha.

Ashwagandha has 48 meta-analyses and 59 randomized trials on PubMed; L-Tryptophan has 18 and 117.

Based on 2,447 reports about Ashwagandha and 238 about L-Tryptophan. Not medical advice.

Ashwagandha
Supplement
L-Tryptophan
Supplement
Users say it helped44%helped1,321 reports · high confidence61%helped67 reports · medium confidence
Verdict
Mixed
Mostly positive
ResearchAResearch: StrongAResearch: Strong
Meta-analyses / RCTs48 / 5918 / 117
Mainly used for
Anxiety
% reporting improvement
88% (881)77% (13)
Mood
% reporting improvement
53% (446)95% (37)
Sleep
% reporting improvement
77% (233)89% (54)
Libido
% reporting improvement
62% (127)—
Energy
% reporting improvement
53% (125)—
Common side effectsanhedonia, drowsiness, fatigue, depressiondrowsiness, vivid dreams, death, anxiety
Typical dose reported800-1600 mg / after dinner1000 mg / before sleep
Ashwagandha
Latest review conclusion

The current systematic review and dose-response meta-analysis of RCTs revealed a beneficial effect in both stress and anxiety following Ashwagandha supplementation. However, further high-quality studies are needed to firmly establish the clinical efficacy of the plant.

Phytother Res, 2022 ↗
What a user said
“I paired it with maca and ashwaganda and it legit felt like a steroid cycle.”
Full Ashwagandha profile →
L-Tryptophan
Latest review conclusion

Trp supplementation, especially at ≥1 g can help improve sleep quality.

Nutr Rev, 2022 ↗
What a user said
“L-Tryptophan has given me the most relaxation / anti-anxiety out of the aminos I've tried.”
Full L-Tryptophan profile →

Related comparisons

Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate