What are the side effects of Vaping Nicotine?

Users most often report vasoconstriction, dehydration, cardiovascular issues, cognitive decline, depression. Side effects came up 8 times across 4 reports.

Vaping Nicotine side effects

Q: Is Vaping Nicotine safe?

User reports can't establish safety. PubMed lists 1 meta-analyses and 5 randomized trials. Talk to a doctor or pharmacist, especially if you take other medication.

Across 4 first-hand reports, people mentioned a side effect 8 times (about 200 per 100 reports). The most common: vasoconstriction, dehydration, cardiovascular issues. User reports show what people notice — they can't tell you whether Vaping Nicotine is safe for you.

Reported side effects

vasoconstriction1

dehydration1

cardiovascular issues1

cognitive decline1

depression1

anxiety1

lung pain1

addiction1

In their own words

“It's absolutely terrible for cardiovascular health. I can feel vasoconstriction happen early in the morning.”

MixedRead the discussion ↗

“I vape (currently trying to quit nicotine) and have experienced minor lung pain in the past”

Didn't helpRead the discussion ↗

Is Vaping Nicotine safe? What the research covers

BResearch: Moderate1 meta-analyses · 5 randomized trials on PubMed

J Bras Nefrol · 2025

Effects of vaping on kidney function: a systematic review on acute kidney injury and chronic kidney disease

Conclusion: Additionally, glomerular damage due to continuous use of vapers has been linked to albuminuria and progression of focal segmental glomerulosclerosis (FSGS), a condition that can lead to CKD. This article highlights the need for further research to clarify the kidney risks associated with vaping and provides information for public health policies on nicotine use.