Tryptophan side effects
Across 149 first-hand reports, people mentioned a side effect 11 times (about 7 per 100 reports). The most common: vivid dreams, anxiety, prolonged effects. User reports show what people notice — they can't tell you whether Tryptophan is safe for you.
Reported side effects
vivid dreams3
anxiety2
prolonged effects1
emotional blunting1
emotional numbness1
disconnection1
brain fog1
drowsiness1
What got worse for some people
In their own words
“I tried St John's Wort, Tryptofan and 5-htp. None worked, it even made the problem subtly worse.”
“1000 mg Tryptophan together, and it was the worst sleep I've had in a loooong time.”
“I know tryptophan and carbohydrates help with this fatigue a little but tryptophan kills my appetite & sometimes motivation a little. After 2-3 days of taking tryptophan I usually start to feel anxious and obsessive”
“I tried raising Serotonin using 5-htp, Tryptophan and eventually St John's Wort. No effect what so ever”
“I tried many things to calm down and be less stressed like ashwagandha, theanine, gaba, tryptophan, passion flower... All of this supplements did not really give me an effect that is so noticeable”
Is Tryptophan safe? What the research covers
AResearch: Strong274 meta-analyses · 818 randomized trials on PubMed
None of the top reviews we found focus on safety. All research on Tryptophan.