Tianeptine Sulfate
People mainly take Tianeptine Sulfate for mood. Based on 10 first-hand reports and 0 meta-analyses & systematic reviews in the medical literature. Ranked #696 of 1,974 overall.
Of reports that state an outcome, 50% are positive.
What Tianeptine Sulfate does, according to users
Of the people who reported each effect, the share who said it got better.
What the research says
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
No randomized controlled trials in humans found on PubMed. The grade measures how much human research exists — read the conclusions below for what it found.
Dosage people report
As stated by users — not a recommendation. Follow the label or your doctor.
Reported side effects
How often each side effect came up across all reports.
What users say
Verbatim quotes, shortened only — each links to the original discussion.
“Later, I try tianeptine sulfate for what I believe is likely moderate-severe depression. The times I took it generally were in the 40-65mg range. Maybe it helps a little, I'm not really sure.”
“in love with this when it was released...lasted the entire day...but after some time the mood-changing effects...faded”
“I prefer this salt form. It is, in overall, better than the sodium. No need to redoes 3 times a day”
Other options for mood
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate