PlainPill

Tau

Based on 3 first-hand reports and 1,912 meta-analyses & systematic reviews in the medical literature. Ranked #2454 of 3,539 overall.

14
User score
Mostly positive
33% positive0% mixed0% negative67% unclear

Of reports that state an outcome, 100% are positive.

Clinical research
AStrong research base
1,912
meta-analyses
2,620
RCTs
77,208
papers

What Tau does, according to users

Of the people who reported each effect, the share who said it got better.

No specific effects reported yet.
betterno changeworse

What the research says

Systematic reviews and meta-analyses from PubMed, with their published conclusions.

AStrong research base

3+ meta-analyses or systematic reviews and 10+ randomized controlled trials in humans. The grade measures how much human research exists — read the conclusions below for what it found.

Lancet Neurol · 2025 · Meta-analysis / systematic review
Blood phosphorylated tau for the diagnosis of Alzheimer's disease: a systematic review and meta-analysis

Conclusion: Plasma p-tau217 is a highly sensitive and specific biomarker for Alzheimer's disease pathology, despite the high risk of bias of many studies. Prospective clinical implementation studies in real-world settings are needed to characterise the effect of plasma p-tau217 on Alzheimer's disease diagnosis and clinical management.

PubMed 40818474 ↗
Lancet Neurol · 2016 · Meta-analysis / systematic review
CSF and blood biomarkers for the diagnosis of Alzheimer's disease: a systematic review and meta-analysis

Conclusion: The core CSF biomarkers of neurodegeneration (T-tau, P-tau, and Aβ42), CSF NFL, and plasma T-tau were strongly associated with Alzheimer's disease and the core biomarkers were strongly associated with mild cognitive impairment due to Alzheimer's disease. Emerging CSF biomarkers NSE, VLP-1, HFABP, and YKL-40 were moderately associated with Alzheimer's disease, whereas plasma Aβ42 and Aβ40 were not. Due to their consistency, T-tau, P-tau, Aβ42, and NFL in CSF should be used in clinical practice and clinical research.

PubMed 27068280 ↗

Dosage people report

As stated by users — not a recommendation. Follow the label or your doctor.

No doses stated in the reports so far.

Reported side effects

How often each side effect came up across all reports.

No side effects reported so far.

What users say

First-hand experiences, quoted verbatim. We show one positive and one negative where both exist.

“AlphaGPC, TAU (triacetyluridine), DHA together. I take them myself and I’ve been giving it to my elderly parents for ~10 years and they are getting smarter.”
HelpedRead the discussion ↗
Top discussions (3)

More supplements

User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 3, 2026. How we rate