Conclusion: Some medications could improve core symptoms, although this could be likely secondary to the improvement of associated symptoms. Evidence on their efficacy and safety is preliminary; therefore, routine prescription of medications for the core symptoms cannot be recommended. Trial registration PROSPERO-ID CRD42019125317.
Sulforaphane side effects
Across 124 first-hand reports, people mentioned a side effect 6 times (about 5 per 100 reports). The most common: stomach issues, anxiety, irritability. User reports show what people notice — they can't tell you whether Sulforaphane is safe for you.
Reported side effects
stomach issues2
anxiety1
irritability1
panic1
impending doom1
In their own words
“sulforaphane, which has helped me a lot, but may not help everyone with anxiety”
Is Sulforaphane safe? What the research covers
AResearch: Strong27 meta-analyses · 73 randomized trials on PubMed
Mol Autism · 2022
Pharmacological and dietary-supplement treatments for autism spectrum disorder: a systematic review and network meta-analysisInt J Mol Sci · 2024
Do Brassica Vegetables Affect Thyroid Function?-A Comprehensive Systematic ReviewConclusion: The vast majority of the results cast doubt on previous assumptions claiming that brassica plants have antithyroid effects in humans. Instead, they indicate that including brassica vegetables in the daily diet, particularly when accompanied by adequate iodine intake, poses no adverse effects on thyroid function.
BMC Psychiatry · 2025
Efficacy and safety of sulforaphane in schizophrenia: a systematic review and meta-analysis of randomized controlled trials