PlainPill

Sulbutiamine

People mainly take Sulbutiamine for energy, mood, focus. Based on 100 first-hand reports and 0 meta-analyses & systematic reviews in the medical literature. Ranked #208 of 1,974 overall.

42
User score
Mixed
24% positive10% mixed8% negative58% unclear

Of reports that state an outcome, 57% are positive.

Clinical research
CLimited research
0
meta-analyses
4
RCTs
36
papers

What Sulbutiamine does, according to users

Of the people who reported each effect, the share who said it got better.

What the research says

Systematic reviews and meta-analyses from PubMed, with their published conclusions.

CLimited research

1–4 randomized controlled trials, no meta-analysis yet. The grade measures how much human research exists — read the conclusions below for what it found.

No meta-analyses or systematic reviews published yet — 4 randomized trials found.

Dosage people report

As stated by users — not a recommendation. Follow the label or your doctor.

100mgdaily
long-termas reported
200 mgdaily
600 mgdaily
1x morning, 1x afternoonas reported
100 mgdaily

Reported side effects

How often each side effect came up across all reports.

headache ×4stomach issues ×2jitteriness ×1b vitamin ×1disinhibition ×1anxiety ×1bizarre thoughts ×1tolerance ×1

What users say

Verbatim quotes, shortened only — each links to the original discussion.

“Sulbutiamine has been shown to increase dopamine receptors through chronic use, so that is one potential route for boosting those receptors.”
Source discussion ↗
“For short periods of time you could try sulbutiamine. 100mg per day is more than enough for me. Effect is subtle like coffee.”
Source discussion ↗
“Combined with Sulbutamine was like a laser cruise control. I feel like a six year old kid in focus terms again.”
Source discussion ↗
“We currently only offer Pramiracetam, Sulbutiamine, Piracetam, Aniracetam, Oxiracetam, Pyritinol, Picamilon, Choline Alpha GPC, Gingko Biloba, and Bacopa Monnieri.”
Source discussion ↗
“Try it too! Not motivated? Dont want to move your fat ass ?... Not a big deal Sulbutiamine will change that!”
Source discussion ↗
Top discussions (5)

Other options for energy

User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate