Benfotiamine vs Sulbutiamine for energy
Short answer: For energy, users rate them about the same: 92% report improvement with Benfotiamine (12 reports) and 94% with Sulbutiamine (86 reports).
Benfotiamine has 5 meta-analyses and 25 randomized trials on PubMed; Sulbutiamine has 0 and 4.
Based on 79 reports about Benfotiamine and 489 about Sulbutiamine. Not medical advice.
| Benfotiamine Supplement | Sulbutiamine Supplement | |
|---|---|---|
| Users say it helped | 82%helped22 reports · medium confidence | 58%helped161 reports · high confidence |
| Verdict | Mostly positive | Mixed |
| Research | AResearch: Strong | CResearch: Limited |
| Meta-analyses / RCTs | 5 / 25 | 0 / 4 |
| Mainly used for | ||
| Energy % reporting improvement | 92% (12) | 94% (86) |
| Focus % reporting improvement | 100% (5) | 89% (46) |
| Mood % reporting improvement | 67% (3) | 76% (46) |
| Anxiety % reporting improvement | — | 85% (20) |
| Memory % reporting improvement | — | 100% (12) |
| Common side effects | fatigue, brain fog, insomnia, chest pain | tolerance, headache, nausea, vomiting |
| Typical dose reported | 80 mg / multiple doses same day | 100mg / daily |
There are only limited data in randomised trials testing the efficacy of vitamin B for treating peripheral neuropathy and the evidence is insufficient to determine whether vitamin B is beneficial or harmful. One small trial in alcoholic peripheral neuropathy reported slightly greater improvement in vibration perception threshold with oral benfotiamine for eight weeks than placebo. In another small study, a higher dose of oral vitamin B complex for four weeks was more efficacious than a lower dose in reducing symptoms and signs. Vitamin B administered by various routes for two to eight weeks wa
Cochrane Database Syst Rev, 2008 ↗“A combination of benfotiamine and sulbutiamine with magnesium greatly improved my erratic movements (twitching, ataxia, shaking hands, etc.) and energy levels.”
“Combined with Sulbutamine was like a laser cruise control. I feel like a six year old kid in focus terms again.”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate